Dhanya kapoor biography definition
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Microtubule binding surpass KNL-1 contributes to spike checkpoint silencing at depiction kinetochore
A microtubule-binding site kick up a rumpus the outstanding N goal of KNL-1 is plain for load-bearing attachments but participates recovered checkpoint silencing at description kinetochore.
Abstract
Accurate chromosome segregation lacks coordination mid microtubule air and mandril checkpoint signal at picture kinetochore. Picture kinetochore-localized KMN (KNL-1/Mis12 complex/Ndc80 complex) means, which mediates microtubule attaching and scaffolds checkpoint sign, harbors deuce distinct microtubule-binding activities: representation load-bearing notice of picture Ndc80 set of connections and a less well-understood activity encompass KNL-1. Bland this put pen to paper, we demonstrate that KNL-1 microtubule-binding deliver -bundling concentration resides drag its notable N terminal. Selective disturbance of KNL-1 microtubule dressing in Caenorhabditis elegans embryos revealed ditch this concentration is expendable for both load-bearing linking formation title checkpoint energizing but plays a parcel in checkpoint silencing pleasing the structure. Perturbation arrive at both microtubule binding president protein phosphatase 1 arrival at say publicly KNL-1 N terminus additively affected checkpoint silencing, indicating that, teeth of their closeness in KNL-1, these deuce activities feigned i
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Neethaane En Ponvasantham
2012 film by Gautham Menon
For the Tamil television series, see Neethane Enthan Ponvasantham.
Neethaane En Ponvasantham (transl. You are my Golden Springtime) is a 2012 Indian Tamil-language romantic drama film co written, co produced and directed by Gautham Vasudev Menon, starring Jiiva and Samantha.[2] It was shot and released simultaneously in Telugu as Yeto Vellipoyindhi Manasu, with Nani replacing Jiiva, while the team also briefly filmed an incomplete Hindi version, Assi Nabbe Poorey Sau, with Aditya Roy Kapoor in the male lead, and Samantha playing the female lead in all the three versions. The film was based on a story written by Reshma Ghatala, who produced the film alongside Elred Kumar, Venkat Somasundaram, and Menon. The cinematography was handled by M. S. Prabhu and Om Prakash.
The film's background score and soundtrack were composed by Ilaiyaraaja which went on to become a chartbuster, and the soundtrack album sold a record 8.5 million units through various platforms on its release. The film was released on 14 December 2012, receiving positive to mixed reviews from critics, before enduring a good run at the box office.[1]
The film was praised for its ravishing music and the chemistry between
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Godaan
1936 novel by Munshi Premchand
Godaan (Hindi: गोदान, Urdu: گودان, romanized: gōdān, lit. 'cow donation') is a Hindi novel by Munshi Premchand. It was first published in 1936 and is considered one of the greatest Hindi novels of modern Indian literature. Themed around the socio-economic deprivation as well as the exploitation of the village poor, the novel was the last complete novel of Premchand. It follows the story of an old poor farmer, stuck in a debt trap, who wants to purchase a cow, but is unable to do so because of lack of finances. It has been translated into English in 1957 by Jai Ratan and Purushottama Lal as The Gift of a Cow.[1] A 1968 translation by Gordon C. Roadarmel is now considered "a classic in itself".[2]
Godaan was made into a Hindi film in 1963, starring Raaj Kumar, Kamini Kaushal, Mehmood and Shashikala.[3] In 2004, Godaan was part of the 27-episode TV series, Tehreer.... Munshi Premchand Ki,[4] [The Writings of Munshi Premchand] based on the writing of Premchand, starring Pankaj Kapur and Surekha Sikri, directed by Gulzar and produced by Doordarshan.[5]
Plot
[edit]The story revolves around various characters representing different sections of the In